Neurodegeneration by Miriam Davis And Clare Stroud, Rapporteurs ; Forum On Neuroscience And Nervous System Disorders, Board On Health Sciences Policy, Institute Of Medicine Of The National Academies

Full Title: Neurodegeneration: Exploring Commonalities Across Diseases Workshop Summary
Author/Editor(s): Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop) ((2012); Miriam Davis; Clare Stroud; Institute of Medicine (U.S.)
ISBN: 0309285674, 9780309285674
Publisher: National Academies Press
Published Place: Washington D C
Published/Copyright Year: 2013
Language: English
Physical Description: Illustrationsustrations (chiefly color) included, 24cm
Number of pages: 106 (106 pages)
Categories:
Nervous System > Degeneration > Congresses
Biology > Research
Neurodegenerative Diseases > Congresses
Biomedical Research > Congresses
Research Design > Congresses


Content:
"Neurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine's (IOM's) Forum on Neuroscience and Nervous System Disorders in Spring 2012 to explore commonalities across neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). Participants from academia; pharmaceutical and biotechnology industries; government agencies such as the National Institutes of Health and the U.S. Department of Veterans Affairs (VA); patient advocacy groups; and private foundations presented and identified potential opportunities for collaboration across the respective research and development communities. This report identifies and discusses commonalities related to genetic and cellular mechanisms, identifies areas of fundamental science needed to facilitate therapeutics development, and explores areas of potential collaboration among the respective research communities. Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, ALS, and FTD, are becoming increasingly prevalent in the United States due to an aging population. Implications are grave for quality of life and health care costs. Research on neurodegenerative diseases has expanded greatly over the past four decades. Nevertheless, fundamental questions remain about the biology of these diseases, and further insights into the mechanisms of these diseases would help to inform the development of effective means to prevent and to efficiently treat them. Recent findings have revealed certain commonalities in genetic and cellular mechanisms across neurodegenerative diseases. These findings suggest that it might be valuable - at least in some cases - to change the traditional way of studying these diseases by no longer seeing each as an independent entity, but rather as clinical variants of common cellular and molecular biological defects. This approach could help enhance basic scientific understanding of neurodegenerative disease, and could help with the development of biomarkers and new therapeutics."
Introduction
Rationale for exploring commonalities across neurodegenerative diseases
Protein aggregation
Transmissibility
Mitochondrial pathology
Errors in RNA
Closing remarks.

Notes:
Includes bibliographical references.

Electronic Resources:
National Academies Press
http://www.nap.edu/catalog.php?record_id=18341

ISBNPlus ID: COL.VX22.34426-data_008-2469632
Other ID: 866949752(OCLC)
Nature: Bibliographies
Form: Nonfiction
LC Call No: R856.A2 N487 2013
Released Date: 20140219

Download BiBTeX of this book (.bib)
@book{isbnplus9780309285674,
 title={Neurodegeneration: Exploring Commonalities Across Diseases  Workshop Summary},
 author={Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop) and Miriam Davis and Clare Stroud and Institute of Medicine (U.S.)},
 isbn={9780309285674},
 url={http://isbnplus.org/9780309285674},
 year={2013},
 publisher={National Academies Press},
 address={Washington  D C}
}
Download 9780309285674.bib
Download EndNote of this book (.enw)
%0 Book
%T Neurodegeneration: Exploring Commonalities Across Diseases  Workshop Summary
%A Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop)
%A Miriam Davis
%A Clare Stroud
%A Institute of Medicine (U.S.)
%@ 9780309285674
%U http://isbnplus.org/9780309285674
%D 2013
%I National Academies Press
%C Washington  D C
Download 9780309285674.enw
Download RefMan of this book (.ris)
TY  - BOOK
T1  - Neurodegeneration: Exploring Commonalities Across Diseases  Workshop Summary
A1  - Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop)
A1  - Miriam Davis
A1  - Clare Stroud
A1  - Institute of Medicine (U.S.)
SN  - 9780309285674
UR  - http://isbnplus.org/9780309285674
Y1  - 2013
PB  - National Academies Press
CY  - Washington  D C
ER  - 
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APA Style:
Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop), Davis, M., Stroud, C. & Institute of Medicine (U.S.) (2013). Neurodegeneration: Exploring Commonalities Across Diseases Workshop Summary. Washington D C: National Academies Press.

MLA Style:
Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop), Miriam Davis, Clare Stroud, and Institute of Medicine (U.S.). Neurodegeneration: Exploring Commonalities Across Diseases Workshop Summary. Washington D C: National Academies Press, 2013. Print.

Chicago Style:
Neurodegeneration: Opportunities for Collaboration Across Disease-Specific Research and Development Communities (Workshop), Miriam Davis, Clare Stroud, and Institute of Medicine (U.S.). Neurodegeneration: Exploring Commonalities Across Diseases Workshop Summary. Washington D C: National Academies Press, 2013.