
The era of Nootropics or Smart Drugs is finally here, you can get dozens of mental health benefits by the products companies have been making to boost mental performance and general IQ level.
But what is it which makes the Nootropic supplement works?
There are plenty of Nootropic substances with great cognition-enhancing effects and there are 6 of them which significantly boost the IQ levels, mental clarity, and focus in a person.
Table of Contents
Define Nootropics
Nootropics are compound or a bunch of supplements that tend to improve the brain’s signaling mechanism hence the brain functions.
This includes every type of ingredient whether natural or manmade including synthetic compounds, vitamins, minerals, and precursors of the neurotransmitters.
Some people believe Nootropic Supplements can actually increase the IQ level which is true as in some people with remarkable brain functions develops this.
How Nootropic Works?
Nootropic in scientific language improves or modulate the processes of neurotransmission and signaling between the cells.
The real purpose of the nootropics is to improve cognition, memory, and learning ability.
The brain after getting numerous vitamins, nutrients and nootropic compound tends to works faster than normal and this gradual process can take weeks or months to establish proper mental clarity and focus.
Top 6 Nootropics in 2021

Every Nootropic supplement must contain the following 6 ingredients which work on different levels.
1) Citicoline
Mostly called Focus Enhancer for Humans, is a naturally occurring compound that mends the neuronal functions and improves cognition.
Citicoline after getting inside the human body converted into Choline which is the real deal for the body.
This Choline is then helpful in the biological synthesis of a neurotransmitter called Acetylcholine.
When Acetylcholine is formed, the levels of attention and focus rises with prompt alertness feature.
The cholinergic system which is involved in this is closely associated with the cognition, memory, and learning process.
In the field of Neuroscience, Citicoline has established a place where it aids cognition and mental function during the stroke.
This feature is not found in many nootropics but Citicoline is majorly subjected to multiple scientific studies. This suffix its safety and efficacy in one.
Studies on Citicoline also show it can benefit the concentration and memory power of a person.
2) Vitamin B-Complex
Enhanced cognition is the result if you take a bunch of Vitamin B complex for a prolonged time.
B Vitamins are good for the health and these are the vitamins which are involved in critical cellular phenomenon without which the body can suffer from plenty of negative conditions.
Speaking of escalated cognition power, B Vitamins ensures there are enough neurons in the brain to function with full potentials.
Some of the major B Vitamins to boost mental clarity and focus are:
Vitamin B1 (Thiamine)
Thiamine is the key ingredient in the metabolic process of Mitochondria. Mitochondria as we learned in schools, is the powerhouse of the cell from which other tissues get their energy from.
In the mitochondrial metabolism, Thiamine or Vitamin B1 play as a cofactor which helps in the production of enzymes that stimulates the neuro-generation.
Thiamine deficiency is dangerous for brain health as it could reduce the cognition power in a person and also increase the chances of neuronal death. Thiamine levels can also affect the levels of GABA or Glutamate which is a reduced state that causes psychiatric disorders.
Studies on Rodents show that Thiamine deficiency on a constant scale can lead to permanent cognitive impairment.
Vitamin B12 (Cobalamin)
Cobalamin is responsible for some heavy machinery in the brain, one of which is the synthesis of DNA and RNA which controls the overall generation and distribution of neurotransmitters.
Vitamin B12 is the key factor in the regulation and sustenance of Myelin, a fatty substance that protects the neurons and use to communicate with others.
The Myelin Sheaths gather the electrical signals from a bunch of neurons and make them work quickly. This defines the communication speed hence the mental dexterity and speed.
3) L-Tyrosine
For the one who would like to be cognitively flexible, L-Tyrosine is one of the amino acids that stimulates the neurotransmitter called Catecholamine.
Catecholamine is the key ingredient for memory boost which is produced inside our body. L-Tyrosine has a strong effect on a person’s mood since it upsurges the level of L-Dopa, the stimulator of the Dopamine hormone.
For the utmost mood stabilization, Dopamine is the key ingredient that makes L-Tyrosine a perfect mood booster.
A double-blind randomized study on the effect of L-Tyrosine claims that adults’ men who took the supplement of L-Tyrosine regularly got their cognition level enhanced and mental flexibility tremendously improved.
The participants were also found out to perform with full mental power with less cognition resource reduction.
L-Tyrosine supplementation enables the multi-task mode in the users who performs daily basis tasks with ease. Some studies suggest L-Tyrosine can help improve memory and basic cognition at the time of undergoing stress.
4) L-Theanine
For mental clarity and relaxation, L-Theanine offers major advantages to the brain just like what Green Tea offers.
The animal studies over the L-Theanine effect show that it can improve memory and cognitive incline in animal models with Alzheimer’s Disease.
A closer inspection, they discovered that L-Theanine is involved in anxiolytic effects that meet the grade for an anti-anxiety medication.
Patients with generalized anxiety disorder reportedly got their symptoms improved after taking L-Theanine supplementation.
Some animal studies show L-Theanine can regulate the levels of Serotonin, GABA, and Dopamine which are all the best mood elevators.
The calming effect brought up by L-Theanine improves the mental concentration and energy it requires to perform multi tasks.
The same effect of L-Theanine is also helpful in improving the sleep cycle to restore the form of Non-Rapid Eye Movement (NREM) sleep.
5) Caffeine
Caffeine is an ultimate CNS stimulant and kicks start for the memory power to some school of thoughts. Without the caffeine-containing beverages, some of us couldn’t get through their day.
It comes under the heading of the best nootropic substance because of its alertness property. Caffeine after alerting the mood can also improve physical endurance and the compound shares a tremendous bioavailability.
On a cellular level, caffeine promotes the learning and memory processing by tampering certain synaptic plasticity.
When the neurons have rigid synaptic plasticity the memory and learning power can be easily enhanced.
Caffeine is beneficial for cognition and alertness but it also has some drawbacks, like anxiety induction and difficulty in sleep.
6) Rhodiola Rosea
One of the most potent natural alternatives to pharmaceutical drugs to protect, repair, and regenerate the neurons.
The nature of Rhodiola Rosea is adaptogenic which is more used in Russian medicine.
In recent years after studying some great nootropics, the medical community around the world enlisted Rhodiola Rosea into the nootropics which help in brain fatigue, concentration, and memory retention.
Some findings of Rhodiola Rosea indicate its efficacy in providing nootropic benefit while other schools of thought are still between the findings.
Which Nootropic Should You Choose?

The best brain boosting supplements must have at least 4 out of 6 ingredients that we mentioned above.
Speaking of which “Mind Lab Pro” contains all 6 of them which is unspeakably miracle to those who’ve lost cognition power for a long time.
The basic ingredients in the Nootropic supplement are natural and most ingredients have scientific literature available by their names.
It can be used by college grade students and adults who are currently fighting with Alzheimer’s Disease, Dementia, and other brain-related conditions that occur at a certain age.
Final Verdict
The domain of neurochemistry is vast and there are always so many things to learn or navigate.
It’s not like you can try the nootropic with any of the ingredients above, do check the company name, reputation, and most of all public reviews about the product.
Neuromodulation is an advanced term that comprises of the top nootropic compounds modulating the overall mental dexterity, clarity, and focus.
Choosing the best nootropics stacks in 2021 could resolve many of your life problems, starting with poor cognition which involves achieving poor grades and demotion at the job.
No one wants to live with a clumsy and lethargic mind and some advanced compounds could eradicate those poor judgmental features of yours in few weeks only.
Mind Lab Pro according to the reviews available online in 2021, helped thousands of people who were mentally fragile and weak at learning, speaking with low mental clarity.
Now they are completely transformed and mentally active.
Thanks to the best Nootropics that helped them boost mental clarity and focus.