How To Compare MODAFINIL Vs ADDERALL In 2024

Adderall is a stimulant with potent properties where as Modafinil is controversial for the treatment of ADHD. Let’s learn what you don’t know about these two!

In this modern and fast world, people have lots of things going on in their minds.

Whether it is personal or professional, people are busy, as they have to reach their desired goal on time.


Students, who have a future ahead and have to make vital decisions in their life for a career, have to study hard in order to gain that target.

Similarly, adults who have a tough job have a lot on their sleeves. To finish the required task, they have to keep their minds going.

This tough life makes our minds slow and weary. There is supplementation for this weakness. Supplements play a vital role in these situations.

Two pills Adderall and Modafinil, are on top of the list. These pills are used to power up the brain and improve cognition, but which pill is best?

Let’s see the difference


Modafinil is a medication that promotes wakefulness.

It is for the treatment of excessive sleepiness caused by sleep apnoea or work sleep disorder.

Modafinil should not be in use if you have any allergic reaction or skin rash. Modafinil might worsen the skin rash that is to be treated only in a hospital.

It is better not to use Modafinil if you have a skin rash, blisters, mouth sore, trouble breathing, fever, swelling in legs, or on the face.


You shall not use Modafinil if you have a skin allergy or skin rash.

To make sure, if Modafinil is safe to consult the doctor and tell him if you have:

  • Angina
  • Liver problem
  • High blood pressure
  • Kidney disease
  • History of mental illness
  • Cardiovascular issue history
  • History of drug addiction
  • Modafinil is addictive. It should never be given or shared with another person, especially with someone with an addictive drug history.
  • If Modafinil is used to treat sleepiness caused by sleep apnoea, then it may also be treated with continuous positive airway pressure (CPAP) machine. This machine is an air pump that gently blows air to the nose with the help of a mask when you are sleeping.


Modafinil may weaken thinking or reaction power. One should be careful when driving or doing anything which needs an alert.

Other than this, Modafinil has some signs of allergic reactions and makes the allergic reactions worse; difficulties in breathing, swelling of face, and legs.

Modafinil can cause skin reactions. Visit your doctor if any of the below signs persists;

  • Skin rash
  • Blisters
  • Fever
  • Shortening of breath
  • Trouble swallowing
  • Swelling in legs
  • Swelling in face, eyes, lips, tongue
  • Stop using Modafinil if you have:
  • Depression
  • Anxiety
  • Suicidal thoughts
  • Hallucination
  • Chest pain
  • Trouble breathing
  • Uneven heartbeats
  • Aggression
  • Unusual behavior
  • Dark urine or jaundice
  • Those are some significant side effects that may cause while using Modafinil.
  • Common side effects include:
  • Headache
  • Dizziness
  • Insomnia
  • Stuffy nose
  • Back pain
  • Feeling nervous
  • Nausea
  • Upset stomach


Adderall is a potent mix of amphetamine and dextroamphetamine.

Amphetamine and dextroamphetamine are stimulants that affect chemicals in the brain and nerves that control impulse control.

Adderall is a pill used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Amphetamine and dextroamphetamine are for other purposes as well.

Adderall may cause psychosis or make it worse if you have psychosis, and especially if you have a history of depression and mental illness.

It may also cause a problem in blood circulation, which may cause numbness, pain, and discoloration in fingers and toes.


Every medicine has some side effects. Some are minor, while others may get significant results.

Other than side effects, doctors warn patients and ask them for their medical history before prescribing any medicine.

Adderall also has some impact. Those who have the below-listed problems should not use it:

  • Glaucoma
  • High blood pressure
  • Overactive thyroid
  • Heart disease
  • Severe anxiety or agitation
  • Vascular disease
  • Artery disease
  • A history of drug or alcohol addiction

Adderall is a stimulant.

Stimulants are a class of drugs which speeds up the message between the brain and body. These stimulants may cause stroke, heart attack, or sudden death.

To make sure Adderall is safe, make sure to tell the doctor about you or anyone in the family has ever had:

  • Depression or anxiety
  • Seizure or epilepsy
  • Liver or kidney disease
  • Blood circulation problem in hands and feet
  • Mental illness or problem with aggression
  • Motor twitches
  • EEG (abnormal brain wave test)

Taking Adderall at times of pregnancy may cause premature birth of the baby or withdrawal symptoms in the newborn baby.

Doctors will decide if you can take Adderall with or without using other medicines.

Adderall may have some reactions when used with other drugs.


It is better not to use it in excess. In case of over dose symptoms may include:

  • Restlessness
  • Tremors
  • Rapid breathing
  • Confusion
  • Hallucinations
  • Panic
  • Vomiting
  • Uneven heartbeat
  • Stomach ache
  • Muscle pain or weakness

Some signs of allergic reactions are the symptoms of Adderall’s side effects.

Other symptoms might include:

  • Heart problem-chest pain, trouble breathing
  • Psychosis- hallucination, behavior problems, aggression
  • Circulation problem- cold feeling, unexplained wounds, pain
  • A seizure
  • Muscle twitches
  • Change in vision
  • Common side effects include:
  • Stomach pain, loss of appetite
  • Weight loss
  • Mood change
  • Fast heart rate
  • Dizziness
  • Insomnia (sleep problem)
  • Dry mouth


Both of these medicines have different usage and effects on our bodies. Make sure to see all the differences before using these medicines.

It is better to use drugs with doctor’s advice. Let’s see the difference between these medicines:


Adderall is a great combo of four different amphetamine salts used for the treatment of narcolepsy and ADHD.

Modafinil is given to those who have problems like sleep apnoea, narcolepsy, and shift work sleep disorder. It may be prescribed for fatigue, depression, ADHD.

People using Adderall for the treatment of ADHD have shown positive effects, and they feel slightly better than before.

People using Modafinil for depression have shown positive results. Modafinil treated depression with energy and focus.

Adderall is a CNS (Central Nervous System) stimulant.

Modafinil is a CNS (Central Nervous System) stimulant.

Common side effects include stomach pain, weight loss, headache, dizziness, sleep problem.

Common side effects include nausea and headache, sleep problem, stuffy nose, back pain, upset stomach.

The quantity of Adderall per bottle is 100 tablets.

The quantity of Modafinil per bottle is 20 each.

Dosage per tablet is 20 mg.

Dosage per tablet is 200 mg.

Adderall is available in the form of a tablet.

Modafinil is available in the form of a tablet.

Cost of Adderall is $744.06

Cost of Modafinil is $345.47

Other brand names of Adderall include Adderall XR, MyDayis.

Another brand name of Modafinil is Provigil.

It takes 34 hours for the concentration of the drug in the body to half of the starting dose.

It takes 15 hours for the concentration of the drug in the body to half of the starting dose.

Adderall has a high potential for mistreatment. Abuse may cause physical and psychological dependence. It has currently given approval for the treatment in the USA.

Modafinil has a low potential for abuse. It has currently given approval in the USA for treatment. Abuse may lead to some degree of physical and psychological dependence.

A total of 174 drugs interact with Adderall.

A total of 385 drugs interact with Modafinil.

Total drugs include 36 major drugs, 130 moderate drugs, and 8 minor drugs.

Total drugs that interact with Modafinil include 34 significant drugs, 178 cheap drugs, and 173 minor drugs.

Using amphetamine with alcohol can increase the risk of cardiovascular diseases, chest pain, or blood pressure changes.

There are no signs of known food or alcohol reactions with Modafinil.

Some diseases might interact when using Adderall, which is cardiovascular, glaucoma, hypertension, liver disease, cardiac disease, agitation, seizure disorders.

Disease interaction of Modafinil is liver disease, hypertension, cardiovascular, seizure disorders, cardiac disease.

Adderall’s first approval date is January 19, 1960

Modafinil’s first approval date is December 24, 1998

Wrap Up

Above is the difference between Modafinil and Adderall.

Both of these medicines are useful for specific purposes, but they should be taken with care and under doctor’s supervision.

It is always better to talk to the doctor before trying or using these nootropic pills as they have different effects on people with various diseases.

These pills are not safe for children. They should be taken under a doctor’s order. Both of these pills have effects which can be major or minor.

However, it is safe to use if necessary. These pills do have a positive impact on people who have been using them.

People are affected by these pills and can vary from person to person.

Prices may differ from the above-mentioned value and may have different effects on people who are using them. Other than these pills, it is better to keep the medicines away from kids.

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