LEADER 04618cam a22004454a 4500
001   2009038904
003 DLC
005 20100521114726.0
008 090917s2010    enkaf    b    001 0 eng  
010   $a  2009038904
015   $aGBA984284$2bnb
016 7 $a101515445$2DNLM
016 7 $a015357051$2Uk
020   $a9780521888745 (hardback)
020   $a0521888743 (hardback)
035   $a(OCoLC)ocn318872041
042   $apcc
050 10$aRC363$b.I54 2010
060 00$a2010 B-203
060 10$aWL 300$bI4347 2010
082 00$a616.8/0471$222
245 00$aInflammatory diseases of the central nervous system /$c[edited by] Trevor Kilpatrick, Richard M. Ransohoff, Steven Wesselingh.
260   $aCambridge ;$aNew York :$bCambridge University Press,$c2010.
300   $aviii, 271 p., [8] p. of plates :$bill. (some col.) ;$c26 cm.
490 1 $aCambridge medicine
504   $aIncludes bibliographical references and index.
505 0 $aInteractions between the immune and nervous systems -- Effectors and determinants of the innate and adaptive immune responses / Edgar Meinl & Hartmut Wekerle -- Microglia: protective and pathogenic mediators / Bevyn Jarrott & Karina Apric? -- The role of dendritic cells in neuro-inflammation / Heather Donaghy, Edwina J. Wright & Anthony L. Cunningham -- Negotiating the brain barriers: access of immune cells and pathogens into the CNS / Britta Engelghardt -- Autoimmunity -- Immune effector heterogeneity in multiple sclerosis and related CNS inflammatory demyelinating disorders Shaunu F. Roemer & Claudia F. Lucchinetti -- Multiple sclerosis : neuro-immune cross-talk in acute and progressive stages of the disease / Martin Kerschensteiner & Reinhard Hohlfeld -- CD8+ T Cell-mediated autoimmune diseases in the CNS / Lisa Walter & Matthew L. Albert -- Acute disseminated encephalomyelitis: determinants and manifestations / Eppie M. Yiu & Andrew J. Kornberg -- Primary angiitis of the CNS and its mimics / Tina Chadha, George F. Duna & Leonard H. Calabrese -- Microbiological and traumatic challenges to the CNS -- Acute viral encephalitis : role of the immune system in viral clearance from the CNS and in the generation of pathology / David N. Irani & Natalie Prow -- Chronic HIV infection of the CNS: role of the immune system in virological control and the generation of pathology / Carolyn F. Orr & Bruce J. Brew -- Brain inflammation during bacterial meningitis / Trine H. Mogensen & Lars Ƙstergaard -- Parasitic infections of the brain: malaria and beyond / Stephen J. Rogerson & Danny A. Milner, Jr -- Role of the inflammatory process in traumatic brain damage / Cristina Morganti-Kossmann ... [et al.] -- Therapy -- HIV-associated neurocognitive disorders: clinical features and therapeutic challenges / Nicoline Schiess & Justin C. McArthur -- Role of immunomodulation in management of infections of the CNS / Miles H. Beaman -- Neuroinflammation: an emerging therapeutic target in neurological disease / Joseph M. Antony & Christopher Power.
520   $a"Interactions between the immune and nervous systems are involved in many disease processes. Modulation of inflammation can provide an important opportunity to enhance regeneration within the central nervous system. This authoritative book defines the key cellular players in mounting an inflammatory response and highlights critical factors in the target organ that influence the nature of that response and its capacity either to damage or protect the brain. Several key clinical areas are highlighted - particularly autoimmune diseases of the nervous system including multiple sclerosis, as well as microbiological and traumatic challenges; the book therefore provides both a summary of the basic science background as well as practical, clinical-friendly guidelines to management. The book will be of interest to a wide range of physicians, including neurologists, neurosurgeons, neurorehabilitationists, infectious disease physicians, and clinical neuroscientists, as well as neuroscientists and immunologists"--Provided by publisher.
650  0$aCentral nervous system$xDiseases.
650  0$aInflammation.
650 12$aCentral Nervous System$ximmunology.
650 22$aCentral Nervous System$xphysiopathology.
650 22$aCentral Nervous System Diseases$ximmunology.
650 22$aInflammation.
650 22$aNeuroimmunomodulation$xphysiology.
700 1 $aKilpatrick, Trevor,$d1959-
700 1 $aRansohoff, Richard M.
700 1 $aWesselingh, Steven.
830  0$aCambridge medicine.